Canary's Tests | Canary Oncoceutics, Inc.

Canary is Developing Three Classes of Tests

Our tests will include DNA only, RNA only or DNA+RNA

Lab Test Comparisons

Test Result	Canary Oncoceutics Canary Acuity	Canary Oncoceutics Canary Lumina	Company A	Company B	Company C	Company D	Company E
# of Genes Analyzed via NGS	1091 (+637 Variants)	DNA + RNA	302	341	517	523	648
Therapeutic SNVs and INDELS	✓	✓	✓	✓	✓	✓	✓
Amplifications and Deletions	✓	✓	✓	✓	✓	✓	✓
Fusions genes	✓	✓	✓	✓	✓	✓	✓
Tumor Mutational Burden (TMB)	✓	✓	✓	✓	✓	✓	✓
Microsatellite Instability (MSI)	✓	✓	✓	✓	✓	✓	✓
TCR Clonality	✓	✓
Homologous Recombination Deficiency (HRD)	✓	✓	✓	✓		✓	✓
Loss of Heterozygosity (LOH)	✓	✓	✓	✓		✓	✓
Comprehensive proprietary database of FDA approved/clinical trial drugs for corresponding biomarkers	✓	✓	✓	✓	✓	✓	✓
Depiction of cancer-relevant pathways	✓	✓
Germline variants affecting drug metabolism	✓	✓
Complete ACMG Oncology Germline Mutational Analysis	✓	✓
ImmunoInsight^TM score (Tumor Immunogenicity)		✓
Tumor Lymphoid Structures Levels (TLS)		✓
Tumor Infiltrating Lymphocytes (TILs)		✓
Therapeutic Response Prediction		✓
Overall Survival Prediction		✓

Tests where Canary has a differentiated advantage

Canary’s Test Provides a Powerful Clinical Advantage

Most up-to-date panel, by far:
Our 1091 gene panelconsists of the ~500 commonly screened genes plus ~600 new genes recently identified as clinically relevant plus 637 variants” (no period at end of sentence).
Therefore, Canary Acuity ^TM provides a dramatic increase in clinical utility for:
- New therapeutic targets
- Drug sensitivity
- Drug resistance
- Drug metabolism

Example of Canary Acuity^TM Benefits in Immunotherapy Testing

Canary Acuity^TM	Company A
Tumor Mutation Burden (1091 genes)”	Tumor Mutation Burden (324 genes)
Microsatellite Instability (1091 genes + 51 markers)	Microsatellite Instability (324 genes)
TCR Clonality (110 genes)	N/A

The more genes sequenced, the more accurate the immunotherapy biomarker predictions

Get In Touch

Address

20 E Thomas Road, Suite 2203, Phoenix, Arizona, 85012, USA

Phone

1-888-909-9809

Email

info@canaryonco.com

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